Clinical Outcomes of Standard Triple Therapy among H. Pylori Infection in Tripoli.

Abstract

The Helicobacter Pylori commonly called H. Pylori infection is one of the common diseases and spread widely among the different classes of society, so that it infects and develops in the stomach and small intestine, and it is a Gram-negative bacillus. The efficacy of standard triple therapy (STT) in treating Helicobacter pylori infection has decreased. Many investigators have tried to increase the suppression rate. The study aimed to discover the clinical results of the usage of triple therapy to eliminate H. Pylori. Methods: this study has been carried between 2^nd of May and 25^th of August on 110 of people have H. Pylori bacteria and treatment with triple therapy aged between 14-60 years, who have applied to Tripoli Medical Centre in Tripoli city, Libya.This study was conducted by Cross Sectional Study. A standard interview-based questionnaire was used to obtain data on personal information such as (age, sex and income level), medical and drug information such as (use triple therapy, duration and side effect of drug). Results: it was discovered that about 75% of patients recovered and improved from H. Pylori after using the triple therapy, and the recent study establish that the meals and females are infected at approximately the same rates, these bacteria can infect at any age, and in this study was also presented about 61.8% of the cases who were infected with H. Pylori depended on fast food, and therefore there is a direct relationship between the type of food and infection with bacteria. Conclusion: From this point view, the triple therapy is a first line of defense, which doctors recommend to treat H. Pylori by Triple therapy (STT= clarithromycin, and amoxicillin or metronidazole).  and must be spread health awareness among people by avoiding fast and unhealthy foods, avoiding stress, anxiety, doing excessive, use of non-steroidal pain-killers, maintaining general and personal hygiene.  Further research in Libya is needed to establish the potential role of standard triple therapy and food in   H. pylori treatments.

Key words: Helicobacter pylori, treatment, standard triple therapy, Libya.